反应详情

温度

80 °C

A mixture of 1.93 g (5.6 mmol) 42A, 840 mg (21 mmol) sodium hydroxide and 25 mL water is stirred for 4 hours at 80° C. The mixture is allowed to cool to room temperature and then neutralized with acetic acid and extracted three times with dichloromethane. The combined organic fractions are dried with sodium sulfate, and the solvent is evaporated in vacuum.

1. temperatureto cool to room temperature
2. extractionextracted three times with dichloromethane
3. dry with materialThe combined organic fractions are dried with sodium sulfate
4. customthe solvent is evaporated in vacuum