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HRID1942422

反应详情

EQUATION

反应方程式

HRID 1942422 的结构方程式

REACTANTS

反应物

3
结构：[I-].[K+]
HCID4875

Potassium iodide

IK

结构：OCCCCl
HCID12313

3-Chloro-1-propanol

C3H7ClO

结构：COc1ccccc1N1CCN(CCO)CC1
HCID11107354

1-Piperazineethanol, 4-(2-methoxyphenyl)-

C13H20N2O2

PRODUCTS

生成物

1
结构：COc1ccccc1N1CCN(CCCO)CC1
HCID410901

未命名化合物

收率 46%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)=O
溶剂HCID180

Acetone

C3H6O

PROCEDURE

实验过程

3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propan-1-ol (29A) is prepared as described for 28A from 3-chloro-propan-1-ol with acetone as solvent and under addition of 1.66 g (10 mmol) potassium iodide. The mixture is heated to reflux.

WORKUP

后处理

  1. temperatureThe mixture is heated to reflux