HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Iodide → 3-(4-(2-Methoxyphenyl)piperazin-1-yl)propan-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | 3-Chloro-1-propanol | HCID 12313 | — |
| Reactant | 1-Piperazineethanol, 4-(2-methoxyphenyl)- | HCID 11107354 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 3-(4-(2-Methoxyphenyl)piperazin-1-yl)propan-1-ol | HCID 410901 | 46% |
Reaction Steps
3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propan-1-ol (29A) is prepared as described for 28A from 3-chloro-propan-1-ol with acetone as solvent and under addition of 1.66 g (10 mmol) potassium iodide. The mixture is heated to reflux.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08389555B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-4605d207bf54446eaa1dc04f83d25558 |
| Source note | uspto-grants-2013_03 |