HCID 67332414, compound → HCID 67331189, compound

Participants

Reaction Steps

To tert-butyl (3R)-3-[{[4-(2-{[(benzyloxy)carbonyl]amino}ethyl)-2,2,7-trimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl]carbonyl}(isopropyl)amino]piperidine-1-carboxylate (1.14 g) were added a 10% palladium carbon (500 mg) and methanol (30 ml), and the mixture was stirred at room temperature under hydrogen atmosphere for 2 hours. After the reaction was complete, the mixture was filtered and concentrated. The obtained residue (900 mg) was used in the subsequent reaction without further treatment.

Provenance & Evidence