1,4-Dioxane hydrochloride → HCID 67331169, compound

Participants

Reaction Steps

To a solution of tert-butyl (3R)-3-[[(4-{2-[(difluoroacetyl)amino]ethyl}-2,2,7-trimethyl-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-6-yl)carbonyl](isopropyl)amino]piperidine-1-carboxylate (1 g) in chloroform (8 ml) was added a 4N hydrochloric acid/dioxane solution (8 ml), and the mixture was stirred at room temperature for one hour. The mixture was concentrated under reduced pressure to give the title compound (0.9 g).

Provenance & Evidence