Methanol → HCID 67331749, compound

Participants

Reaction Steps

To a solution of tert-butyl (3R)-3-[isopropyl({7-methyl-3-oxo-4-[2-(propionylamino)ethyl]-3,4-dihydrospiro[1,4-benzothiazine-2,1′-cyclobutan]-6-yl}carbonyl)amino]piperidine-1-carboxylate (2.5 g) in chloroform (7 ml)-methanol (15 ml) was added a 4N hydrochloric acid/dioxane solution (21 ml), and the mixture was stirred at room temperature for one hour. The mixture was concentrated under reduced pressure to give the title compound (2.2 g).

Provenance & Evidence