HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-2-(Methylamino)-2-phenylethanol → HCID 59278674, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-2-(Methylamino)-2-phenylethanol | HCID 11030005 | — |
| Reactant | (4-Chloro-6-methoxy-[1,3,5]triazin-2-yl)-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-amine | HCID 86640783 | — |
| Product | HCID 59278674 | HCID 59278674 | 32% |
Reaction Steps
This compound was prepared from (4-chloro-6-methoxy-[1,3,5]triazin-2-yl)-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-amine and (R)-2-methylamino-2-phenyl-ethanol in analogy to example 1c. Purification by chromatography on Si—NH2 gel (Isolute) using ethyl acetate as an eluent gave the title compound as a colorless solid in 32% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08389717B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-ffc93e33f0c448c68b2d505ecbb3e869 |
| Source note | uspto-grants-2013_03 |