1-Methylimidazole → HCID 46834773, compound

HRID 1943309Notes

Reaction equation

HRID 1943309 reaction equation
[CH3:1][N:2]1[CH:6]=[CH:5][N:4]=[CH:3]1.[Br:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]2[O:16][C:17]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)=[CH:18][N:19]=2)=[CH:11][CH:10]=1>C1COCC1>[Br-:7].[CH3:1][N+:2]1[CH:6]=[CH:5][N:4]([CH2:8][C:9]2[CH:10]=[CH:11][C:12]([C:15]3[O:16][C:17]([C:20]4[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=4)=[CH:18][N:19]=3)=[CH:13][CH:14]=2)[CH:3]=1

Participants

4

Reactant 2

HCID 13901-MethylimidazoleHCID 122501072-(4-bromomethyl-phenyl)-5-phenyl-oxazole

Product 1

HCID 46834773HCID 46834773, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

To a round-bottomed flask previously purged with anhydrous argon are added 1-methylimidazole (Aldrich) (0.257 mL, 0.265 g, 3.2 mmol), 2-(4-bromomethyl-phenyl)-5-phenyl-oxazole [1] (1.013 g, 3.224 mmol) and anhydrous THF (15 mL).

Workup

  1. customTo a round-bottomed flask previously purged with anhydrous argon

Sources & evidence

ORD record
ord-e5458b72f25f4625a95e2bf006acb2c5
Source dataset
uspto-grants-2013_03
Patent number
US08389940B2

Reaction notes

Loading…