Boron tribromide → HCID 44610443, compound

Participants

Reaction Steps

By the same method as in the step b) of Example 12, (2,3-dihydro-pyrido[3,4-b][1,4]oxazin-1-yl)-(4-methoxy-3-trifluoromethyl-phenyl)-methanone (110 mg, 0.325 mmol) was reacted with 1M solution of boron tribromide (3.25 ml, 3.25 mmol) to obtain the target compound, (2,3-dihydro-pyrido[3,4-b][1,4]oxazin-1-yl)-(4-hydroxy-3-trifluoromethyl-phenyl)-methanone, as white solid (11 mg, 10%).

Provenance & Evidence