Boron tribromide → HCID 44608382, compound

Participants

Reaction Steps

By the same method as in Example 3, (3-bromo-4-methoxy-phenyl)-(2,3-dihydro-pyrido[3,4-b][1,4]oxazin-1-yl)-methanone (200 mg, 0.58 mmol) and 1M solution of boron tribromide (2.9 ml, 2.9 mmol)) were reacted to obtain the target compound 40, i.e., (3-bromo-4-hydroxy-phenyl)-(2,3-dihydro-pyrido[3,4-b][1,4]oxazin-1-yl)-methanone, as beige solid (95 mg, 49%).

Provenance & Evidence