HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl bromopyruvate → HCID 66863389, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl bromopyruvate | HCID 66144 | — |
| Reactant | HCID 66863244 | HCID 66863244 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 66863389 | HCID 66863389 | 67.8% |
Reaction Steps
The compound is prepared according to a process similar to that described in step 15.3, by reacting 0.23 g (0.54 mmol) of N-[2-aminopyrid-4-yl]-5-trifluoromethyl-1-[(3-fluorophenyl)methyl]-1H-indole-2-carboxamide, prepared according to the protocol described in step 17.2, with 0.21 g (1.07 mmol) of ethyl 3-bromo-2-oxopropionate in 4 mL of acetonitrile. 192 mg of the expected product are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08394820B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-756d8ed3f4d64b999dae7fc919a17482 |
| Source note | uspto-grants-2013_03 |