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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1944009Generated: October 30, 2026

Ethyl bromopyruvate → HCID 66863389, compound

https://huagongshe.com/reaction/1944009

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl bromopyruvateHCID 66144—
ReactantHCID 66863244HCID 66863244—
SolventAcetonitrileHCID 6342—
ProductHCID 66863389HCID 6686338967.8%

Reaction Steps

The compound is prepared according to a process similar to that described in step 15.3, by reacting 0.23 g (0.54 mmol) of N-[2-aminopyrid-4-yl]-5-trifluoromethyl-1-[(3-fluorophenyl)methyl]-1H-indole-2-carboxamide, prepared according to the protocol described in step 17.2, with 0.21 g (1.07 mmol) of ethyl 3-bromo-2-oxopropionate in 4 mL of acetonitrile. 192 mg of the expected product are obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08394820B2
Source datasetuspto-grants-2013_03
ORD IDord-756d8ed3f4d64b999dae7fc919a17482
Source noteuspto-grants-2013_03