HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 22997467, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Ethylmorpholine | HCID 7525 | — |
| Reactant | O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733207 | — |
| Product | HCID 22997467 | HCID 22997467 | — |
Reaction Steps
To a mixture of the product of example 1i (220 mg) and the product of example 23a (145 mg) in DMF (1.5 ml) was added N-ethylmorpholine (100 μl) and TBTU (200 mg). The reaction mixture was stirred at room temperature for 2 h. Water (5 ml) was added, followed by filtration and drying of the precipitate. Trituration with heptane/diisopropylether afforded the product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08394789B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-5e2aeadaa7d445388f4ecb98bd5b71ab |
| Source note | uspto-grants-2013_03 |