反应详情

To a mixture of the product of example 1i (220 mg) and the product of example 23a (145 mg) in DMF (1.5 ml) was added N-ethylmorpholine (100 μl) and TBTU (200 mg). The reaction mixture was stirred at room temperature for 2 h. Water (5 ml) was added, followed by filtration and drying of the precipitate. Trituration with heptane/diisopropylether afforded the product.

1. filtrationfollowed by filtration
2. customdrying of the precipitate