HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluoro-4-nitrobenzamide → 4-Amino-2-fluoro-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluoro-4-nitrobenzamide | HCID 21784094 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Palladium | HCID 23938 | — |
| Product | 4-Amino-2-fluoro-benzamide | HCID 23068005 | — |
Reaction Steps
2-fluoro-4-nitrobenzamide (E335) was dissolved in EtOH under Ar and 10% Pd/C added. The reaction was pump-purged with H2 and left stirring at room temperature overnight. The catalyst was removed by filtration and the reaction concentrated to give pure 4-amino-2-fluorobenzamide (E336).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08394826B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-ff1e2b95a72d4361b847f2e368d3c0c1 |
| Source note | uspto-grants-2013_03 |