Methyl bromoacetate → HCID 67456764, compound

HRID 1944311Notes

Reaction equation

HRID 1944311 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][C:5]([OH:26])=[C:6]2[C:11]=1[NH:10][C:9](=[O:12])[C:8]([CH2:13][C:14]1[CH:19]=[CH:18][C:17]([N:20]3[CH:24]=[CH:23][CH:22]=[N:21]3)=[CH:16][CH:15]=1)=[C:7]2[CH3:25].[CH3:27][O:28][C:29](=[O:32])[CH2:30]Br>>[CH3:27][O:28][C:29](=[O:32])[CH2:30][O:26][C:5]1[CH:4]=[CH:3][C:2]([F:1])=[C:11]2[C:6]=1[C:7]([CH3:25])=[C:8]([CH2:13][C:14]1[CH:19]=[CH:18][C:17]([N:20]3[CH:24]=[CH:23][CH:22]=[N:21]3)=[CH:16][CH:15]=1)[C:9](=[O:12])[NH:10]2

Participants

3

Reactant 2

HCID 60984Methyl bromoacetateHCID 67459011HCID 67459011, compound

Product 1

HCID 67456764HCID 67456764, compound

Procedure

The title compound was prepared by the method of Preparation 7a using 8-fluoro-5-hydroxy-4-methyl-3-(4-pyrazol-1-ylbenzyl)-1H-quinolin-2-one and bromoacetic acid methyl ester.

Sources & evidence

ORD record
ord-c76fe718d2304a39a72e1e9f201cac4c
Source dataset
uspto-grants-2013_03
Patent number
US08394830B2

Reaction notes

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