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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1944317Generated: October 26, 2026

Methyl 2-(3-amino-4-chlorophenoxy)acetate → [8-Chloro-2-ethyl-3-(4-isobutyrylbenzyl)-4-oxo-1,4-dihydroquinolin-5-yloxy]acetic acid methyl ester

https://huagongshe.com/reaction/1944317

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(3-amino-4-chlorophenoxy)acetateHCID 66717604—
Reactant2-(4-Isobutyrylbenzyl)-3-oxopentanoic acid ethyl esterHCID 67458290—
Product[8-Chloro-2-ethyl-3-(4-isobutyrylbenzyl)-4-oxo-1,4-dihydroquinolin-5-yloxy]acetic acid methyl esterHCID 67456772—

Reaction Steps

The title compound was prepared by the method of Preparation 1c using (3-amino-4-chlorophenoxy)acetic acid methyl ester and 2-(4-isobutyrylbenzyl)-3-oxopentanoic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08394830B2
Source datasetuspto-grants-2013_03
ORD IDord-0b4be07a8035409a95f6b19a139bc684
Source noteuspto-grants-2013_03