Methyl bromoacetate → HCID 67456375, compound

HRID 1944326Notes

Reaction equation

[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([OH:27])=[C:6]2[C:11]=1[NH:10][C:9](=[O:12])[C:8]([CH2:13][C:14]1[CH:19]=[CH:18][C:17]([C:20](=[O:25])[C:21]([CH3:24])([CH3:23])[CH3:22])=[CH:16][CH:15]=1)=[C:7]2[CH3:26].[CH3:28][O:29][C:30](=[O:33])[CH2:31]Br>>[CH3:28][O:29][C:30](=[O:33])[CH2:31][O:27][C:5]1[CH:4]=[CH:3][C:2]([Cl:1])=[C:11]2[C:6]=1[C:7]([CH3:26])=[C:8]([CH2:13][C:14]1[CH:19]=[CH:18][C:17]([C:20](=[O:25])[C:21]([CH3:23])([CH3:22])[CH3:24])=[CH:16][CH:15]=1)[C:9](=[O:12])[NH:10]2

Participants

Reactant 2

HCID 60984Methyl bromoacetate

HCID 67458097HCID 67458097, compound

Product 1

HCID 67456375HCID 67456375, compound

Procedure

The title compound was prepared by the method of Preparation 7a using 8-chloro-3-[4-(2,2-dimethylpropionyl)benzyl]-5-hydroxy-4-methyl-1H-quinolin-2-one and bromoacetic acid methyl ester.

Sources & evidence

ORD record: ord-b78e16e3e96f47c3bcc2daa10cbdfda0
Source dataset: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08394830B2

Reaction notes

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