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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1944392Generated: November 1, 2026

HCID 67044881, compound → HCID 86652183, compound

https://huagongshe.com/reaction/1944392

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67044881HCID 67044881—
CatalystHCID 178418406HCID 178418406—
SolventChloroformHCID 6212—
ProductHCID 86652183HCID 8665218366.2%

Reaction Conditions

Temperature60 °C

Reaction Steps

A solution of N-(4-fluorophenyl)-2-hydroxymethyl-N-methylbenzenesulfonamide (0.35 g) in chloroform (20 mL) was treated with manganese dioxide (1.2 g), and the resulting mixture was stirred at 60° C. for 16 hours. The mixture was filtered through Celite and the filtrate concentrated under reduced pressure to afford the title compound as colourless oil (0.23 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08394836B2
Source datasetuspto-grants-2013_03
ORD IDord-f5edb48802e94d7ebbac2029e66ee876
Source noteuspto-grants-2013_03