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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1944395Generated: October 26, 2026

Methyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetate → {5-Fluoro-3-[3-(4-fluorobenzenesulfonyl)pyridin-2-ylmethyl]-2-methylindol-1-yl}acetic acid methyl ester

https://huagongshe.com/reaction/1944395

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetateHCID 58247161—
Reactant3-(4-Fluorobenzenesulfonyl)pyridine-2-carbaldehydeHCID 86652184—
Product{5-Fluoro-3-[3-(4-fluorobenzenesulfonyl)pyridin-2-ylmethyl]-2-methylindol-1-yl}acetic acid methyl esterHCID 67044579—

Reaction Steps

The title compound was prepared by the method of Preparation 1c using (5-fluoro-2-methylindol-1-yl)acetic acid methyl ester and 3-(4-fluorobenzenesulfonyl)pyridine-2-carbaldehyde.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08394836B2
Source datasetuspto-grants-2013_03
ORD IDord-8cc71d95efa847b5b11caf2047b8b095
Source noteuspto-grants-2013_03