HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetate → [3-(5-Benzenesulfonylthiazol-4-ylmethyl)-5-fluoro-2-methylindol-1-yl]acetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetate | HCID 58247161 | — |
| Reactant | 5-(Phenylsulfonyl)-4-thiazolecarboxaldehyde | HCID 86652201 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | [3-(5-Benzenesulfonylthiazol-4-ylmethyl)-5-fluoro-2-methylindol-1-yl]acetic acid methyl ester | HCID 67045020 | — |
Reaction Steps
The title compound was prepared by the method of Preparation 1c using (5-fluoro-2-methylindol-1-yl)acetic acid methyl ester and 5-benzenesulfonylthiazole-4-carbaldehyde in dichloromethane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08394836B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-e86bb7b420e54aab99e490c482271d76 |
| Source note | uspto-grants-2013_03 |