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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1944487Generated: October 29, 2026

Methyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetate → {3-[5-Chloro-3-(pyridine-2-sulfonyl)thiophen-2-ylmethyl]-5-fluoro-2-methylindol-1-yl}acetic acid methyl ester

https://huagongshe.com/reaction/1944487

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetateHCID 58247161—
Reactant5-Chloro-3-(pyridine-2-sulfonyl)thiophene-2-carbaldehydeHCID 86652210—
Product{3-[5-Chloro-3-(pyridine-2-sulfonyl)thiophen-2-ylmethyl]-5-fluoro-2-methylindol-1-yl}acetic acid methyl esterHCID 67044933—

Reaction Steps

The title compound was prepared by the method of Preparation 42b using 5-chloro-3-(pyridine-2-sulfonyl)thiophene-2-carbaldehyde and (5-fluoro-2-methylindol-1-yl)acetic acid methyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08394836B2
Source datasetuspto-grants-2013_03
ORD IDord-746249130ace4839a33d76dcc61e27aa
Source noteuspto-grants-2013_03