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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1944489Generated: October 25, 2026

Methyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetate → [3-(3-Benzenesulfonyl-5-chlorothiophen-2-ylmethyl)-5-fluoro-2-methylindol-1-yl]acetic acid methyl ester

https://huagongshe.com/reaction/1944489

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(5-fluoro-2-methyl-1H-indol-1-yl)acetateHCID 58247161—
Reactant3-Benzenesulfonyl-5-chlorothiophene-2-carbaldehydeHCID 86652211—
Product[3-(3-Benzenesulfonyl-5-chlorothiophen-2-ylmethyl)-5-fluoro-2-methylindol-1-yl]acetic acid methyl esterHCID 67044830—

Reaction Steps

The title compound was prepared by the method of Preparation 42b using 3-benzenesulfonyl-5-chlorothiophene-2-carbaldehyde and (5-fluoro-2-methylindol-1-yl)acetic acid methyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08394836B2
Source datasetuspto-grants-2013_03
ORD IDord-36ac6881062c44a1abe842fabd590832
Source noteuspto-grants-2013_03