1H-Indazole → HCID 58506951, compound

Participants

Reaction Conditions

Reaction Steps

Referring to Scheme 1, a mixture of indazole (450 mg, 3.86 mmol) and 2-bromo-4-methylpentanoic acid (1.5 eq.) was heated to 160° C. for 4 hours. The mixture was cooled, diluted with water, extracted by EtOAc, and dried over MgSO4. The solvent was then removed to give the crude product, which was used for the next step without further purification. [M+H] calc'd for C14H16N2O4, 233; found, 233.

Provenance & Evidence