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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1944721Generated: October 27, 2026

Ethyl 4-(1,3-dioxoisoindolin-2-yl)-1-methylcyclohexanecarboxylate → 1-Allyl-4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-cyclohexanecarboxylic acid ethyl ester

https://huagongshe.com/reaction/1944721

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 4-(1,3-dioxoisoindolin-2-yl)-1-methylcyclohexanecarboxylateHCID 58074352—
ReactantEthyl 1-allyl-4-hydroxycyclohexanecarboxylateHCID 67225352—
Product1-Allyl-4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-cyclohexanecarboxylic acid ethyl esterHCID 67225098—

Reaction Steps

The title compound was prepared by a method analogous to the method used to prepare Intermediate 72 using ethyl 1-allyl-4-hydroxycyclohexanecarboxylate (Intermediate 99) as the starting material.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08394858B2
Source datasetuspto-grants-2013_03
ORD IDord-6cd81255fb534f338c703b43c55ce99e
Source noteuspto-grants-2013_03