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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1944906Generated: October 30, 2026

Methyl 4-(4'-amino-[1,1'-biphenyl]-4-yl)butanoate → Methyl 4-(4'-(3-((3-carbamoyl-4-((3-methoxyphenyl)amino)-8-methylquinolin-6-yl)sulfonyl)benzamido)-[1,1'-biphenyl]-4-yl)butanoate

https://huagongshe.com/reaction/1944906

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-(4'-amino-[1,1'-biphenyl]-4-yl)butanoateHCID 57516934—
Reactant6-[[3-[(8-Hydroxyoctyl)carbamoyl]phenyl]sulfonyl]-4-[(3-methoxyphenyl)amino]-8-methylquinoline-3-carboxamideHCID 66988028—
ProductMethyl 4-(4'-(3-((3-carbamoyl-4-((3-methoxyphenyl)amino)-8-methylquinolin-6-yl)sulfonyl)benzamido)-[1,1'-biphenyl]-4-yl)butanoateHCID 66988342—

Reaction Steps

The title compound was synthesized in a manner analogous to that described for Intermediate 70, using Intermediate 29 in place of 8-aminooctanol. ES/MS calcd. for C42H39N4O7S+ 743.3. Found m/z=743.4 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08394829B2
Source datasetuspto-grants-2013_03
ORD IDord-bf6d36d5bcb042ea9cc36f317f7d6ae0
Source noteuspto-grants-2013_03