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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1944911Generated: November 1, 2026

6-((3-((4'-(4-Hydroxybutyl)-[1,1'-biphenyl]-4-yl)carbamoyl)phenyl)sulfonyl)-4-((3-methoxyphenyl)amino)-8-methylquinoline-3-carboxamide → 6-((3-((4'-(4-Hydroxybutyl)-(1,1'-biphenyl]-3-yl)carbamoyl)phenyl)sulfonyl)-4-((3-methoxyphenyl)amino)-8-methylquinoline-3-carboxamide

https://huagongshe.com/reaction/1944911

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-((3-((4'-(4-Hydroxybutyl)-[1,1'-biphenyl]-4-yl)carbamoyl)phenyl)sulfonyl)-4-((3-methoxyphenyl)amino)-8-methylquinoline-3-carboxamideHCID 66988346—
ReactantMethyl 4-(3'-(3-((3-carbamoyl-4-((3-methoxyphenyl)amino)-8-methylquinolin-6-yl)sulfonyl)benzamido)-[1,1'-biphenyl]-4-yl)butanoateHCID 66988954—
Product6-((3-((4'-(4-Hydroxybutyl)-(1,1'-biphenyl]-3-yl)carbamoyl)phenyl)sulfonyl)-4-((3-methoxyphenyl)amino)-8-methylquinoline-3-carboxamideHCID 66988140—

Reaction Steps

The title compound was synthesized in a manner analogous to that described for Intermediate 90, using Intermediate 87 as a substrate. ES/MS calcd. for C41H39N4O6S+ 715.3. Found m/z=715.4 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08394829B2
Source datasetuspto-grants-2013_03
ORD IDord-675db68bbcc641308e17afae68ad4403
Source noteuspto-grants-2013_03