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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1944925Generated: October 25, 2026

1-(4-((6-Bromohexyl)oxy)butyl)-4-nitrobenzene → (R)-8-hydroxy-5-(2,2,3,3-tetramethyl-18-(4-nitrophenyl)-4,14-dioxa-7-aza-3-silaoctadecan-5-yl)quinolin-2(1H)-one

https://huagongshe.com/reaction/1944925

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-((6-Bromohexyl)oxy)butyl)-4-nitrobenzeneHCID 20071424—
ReactantHCID 58505093HCID 58505093—
Product(R)-8-hydroxy-5-(2,2,3,3-tetramethyl-18-(4-nitrophenyl)-4,14-dioxa-7-aza-3-silaoctadecan-5-yl)quinolin-2(1H)-oneHCID 58505188—

Reaction Steps

The title compound was synthesized in a manner analogous to that described for Intermediate 102, using Intermediate 52 in place of Intermediate 45. ES/MS calcd. for C33H50N3O6Si+ 612.4. Found m/z=612.5 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08394829B2
Source datasetuspto-grants-2013_03
ORD IDord-51a38937c26340a3bfc8825a142d9f3c
Source noteuspto-grants-2013_03