HRID1944971

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1cccc(Nc2c(C(N)=O)cnc3c(C)cc(S(=O)(=O)c4cccc(C(=O)N(C)CCCCCC=O)c4)cc23)c1

HCID86659092

未命名化合物

结构：COc1cccc(Nc2c(C(N)=O)cnc3c(C)cc(S(=O)(=O)c4cccc(C(=O)Nc5ccc(-c6ccc(CCCCNC[C@H](O[Si](C)(C)C(C)(C)C)c7ccc(O)c8c7OCC(=O)N8)cc6)cc5)c4)cc23)c1

HCID86659117

未命名化合物

PRODUCTS

生成物

结构：COc1cccc(Nc2c(C(N)=O)cnc3c(C)cc(S(=O)(=O)c4cccc(C(=O)N(C)CCCCCCNC[C@H](O[Si](C)(C)C(C)(C)C)c5ccc(O)c6c5OCC(=O)N6)c4)cc23)c1

HCID87226372

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized in a manner analogous to that described in Intermediate 151, using Intermediate 114 in place of Intermediate 124. ES/MS calcd. C48H60N6O9SSi 942.4. Found m/z=925 (M+H)+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-01edf245ff04416e959d47262c750eca
来源数据集: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08394829B2
来源说明: uspto-grants-2013_03

反应 SMILES

[Si:1]([O:8][C@H:9]([C:63]1[C:68]2[O:69][CH2:70][C:71](=[O:73])[NH:72][C:67]=2[C:66]([OH:74])=[CH:65][CH:64]=1)[CH2:10][NH:11][CH2:12][CH2:13][CH2:14]CC1C=CC(C2C=CC(NC(C3C=C(S(C4C=C5C(=C(C)C=4)N=CC(C(N)=O)=C5NC4C=CC=C(OC)C=4)(=O)=O)C=CC=3)=O)=CC=2)=CC=1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].[CH3:75][O:76][C:77]1[CH:78]=[C:79]([NH:83][C:84]2[C:93]3[C:88](=[C:89]([CH3:114])[CH:90]=[C:91]([S:94]([C:97]4[CH:102]=[CH:101][CH:100]=[C:99]([C:103](=[O:113])[N:104]([CH3:112])[CH2:105][CH2:106][CH2:107]CCC=O)[CH:98]=4)(=[O:96])=[O:95])[CH:92]=3)[N:87]=[CH:86][C:85]=2[C:115]([NH2:117])=[O:116])[CH:80]=[CH:81][CH:82]=1>>[Si:1]([O:8][C@H:9]([C:63]1[C:68]2[O:69][CH2:70][C:71](=[O:73])[NH:72][C:67]=2[C:66]([OH:74])=[CH:65][CH:64]=1)[CH2:10][NH:11][CH2:12][CH2:13][CH2:14][CH2:107][CH2:106][CH2:105][N:104]([CH3:112])[C:103]([C:99]1[CH:98]=[C:97]([S:94]([C:91]2[CH:92]=[C:93]3[C:88](=[C:89]([CH3:114])[CH:90]=2)[N:87]=[CH:86][C:85]([C:115]([NH2:117])=[O:116])=[C:84]3[NH:83][C:79]2[CH:80]=[CH:81][CH:82]=[C:77]([O:76][CH3:75])[CH:78]=2)(=[O:96])=[O:95])[CH:102]=[CH:101][CH:100]=1)=[O:113])([C:4]([CH3:5])([CH3:6])[CH3:7])([CH3:2])[CH3:3]