HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86659092, compound → (R)-6-((3-((6-((2-((tert-butyldimethylsilyl)oxy)-2-(5-hydroxy-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-8-yl)ethyl)amino)hexyl)(methyl)carbamoyl)phenyl)sulfonyl)-4-((3-methoxyphenyl)amino)-8-methylquinoline-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86659092 | HCID 86659092 | — |
| Reactant | (R)-6-((3-((4'-(4-((2-((tert-butyldimethylsilyl)oxy)-2-(5-hydroxy-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-8-yl)ethyl)amino)butyl)-[1,1'-biphenyl]-4-yl)carbamoyl)phenyl)sulfonyl)-4-((3-methoxyphenyl)amino)-8-methylquinoline-3-carboxamide | HCID 86659117 | — |
| Product | (R)-6-((3-((6-((2-((tert-butyldimethylsilyl)oxy)-2-(5-hydroxy-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-8-yl)ethyl)amino)hexyl)(methyl)carbamoyl)phenyl)sulfonyl)-4-((3-methoxyphenyl)amino)-8-methylquinoline-3-carboxamide | HCID 87226372 | — |
Reaction Steps
The title compound was synthesized in a manner analogous to that described in Intermediate 151, using Intermediate 114 in place of Intermediate 124. ES/MS calcd. C48H60N6O9SSi 942.4. Found m/z=925 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08394829B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-01edf245ff04416e959d47262c750eca |
| Source note | uspto-grants-2013_03 |