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HRID1945054

反应详情

EQUATION

反应方程式

HRID 1945054 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)C(F)(F)F
HCID6422

未命名化合物

结构：COC(=O)C(CC(=O)OC(C)(C)C)Cc1ccc(-c2ccccc2)cc1
HCID68424697

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)C(CC(=O)O)Cc1ccc(-c2ccccc2)cc1
HCID59607829

未命名化合物

PROCEDURE

实验过程

Next, 2-biphenyl-4-ylmethyl-succinic acid 4-tert-butyl ester 1-methyl ester (160 mg, 0.451 mmol) is added to trifluoroacetic acid (5 mL). After 10 minutes, the solvent is removed under reduced pressure. Methylene chloride is added and the solvent is removed under reduced pressure to give 2-biphenyl-4-ylmethyl-succinic acid 1-methyl ester. This material is used directly in the subsequent coupling reaction.

WORKUP

后处理

  1. customthe solvent is removed under reduced pressure
  2. additionMethylene chloride is added
  3. customthe solvent is removed under reduced pressure