Bromine → HCID 59350852, compound

HRID 1945188Notes

Reaction equation

HRID 1945188 reaction equation
[Br:1]Br.[CH2:3]([S:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([CH3:12])[CH:7]=1)[CH3:4]>C(O)(=O)C>[Br:1][C:9]1[CH:10]=[CH:11][C:6]([S:5][CH2:3][CH3:4])=[CH:7][C:8]=1[CH3:12]

Participants

4

Reactant 2

HCID 24408BromineHCID 141922Benzene, 1-(ethylthio)-3-methyl-

Product 1

HCID 59350852HCID 59350852, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Bromine (2.2 ml) was added to a solution of 1-(ethylthio)-3-methylbenzene (6.6 g) in acetic acid (20 ml) at 0° C. The mixture was stirred at RT for 2 h then the solvent removed under reduced pressure. The residue was purified by chromatography on silica eluting with DCM. Yield 6.6 g

Workup

  1. customthe solvent removed under reduced pressure
  2. customThe residue was purified by chromatography on silica eluting with DCM

Sources & evidence

ORD record
ord-206ccd3d7dc44eb7be592aa4a6634e44
Source dataset
uspto-grants-2013_03
Patent number
US08394986B2

Reaction notes

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