m-Chloroperbenzoic acid → HCID 86659306, compound

HRID 1945200Notes

Reaction equation

HRID 1945200 reaction equation
ClC1C=C(C=CC=1)C(OO)=[O:6].[Cl:12][C:13]1[CH:27]=[CH:26][C:16]([O:17][CH2:18][C:19]([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20])=[C:15]([S:28][C:29]2[CH:34]=[CH:33][C:32]([S:35]([CH3:38])(=[O:37])=[O:36])=[CH:31][CH:30]=2)[CH:14]=1>C(Cl)Cl>[Cl:12][C:13]1[CH:27]=[CH:26][C:16]([O:17][CH2:18][C:19]([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20])=[C:15]([S:28]([C:29]2[CH:30]=[CH:31][C:32]([S:35]([CH3:38])(=[O:36])=[O:37])=[CH:33][CH:34]=2)=[O:6])[CH:14]=1

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 86659307HCID 86659307, compound

Product 1

HCID 86659306HCID 86659306, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Conditions

Temperature
0 °C

Procedure

3-Chloroperoxybenzoic acid (70% purity, 0.2 g) was added to a solution of the product from example 9 step (ii) (0.35 g) in DCM (10 ml) and stirred at 0° C. for 1 h. The mixture was partitioned between DCM/aq. sodium metabisulphite solution, the organics washed with aq. sodium hydrogencarbonate solution, water, dried and evaporated under reduced pressure. Yield 0.34 g

Workup

  1. customThe mixture was partitioned between DCM/aq
  2. washsodium metabisulphite solution, the organics washed with aq. sodium hydrogencarbonate solution, water
  3. customdried
  4. customevaporated under reduced pressure

Sources & evidence

ORD record
ord-46ecae05040d4762ac7bc9a16785ea45
Source dataset
uspto-grants-2013_03
Patent number
US08394986B2

Reaction notes

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