反应详情

温度

70 °C

8.5 mg (0.03 mmol) of 2-iodobenzenesulfonic acid prepared by Preparation Example 1, 1.48 g (2.4 mmol) of Oxone (registered trademark) and 433 mg (3 mmol) of 5-nonanol were added to 3.75 ml ethyl acetate, and the mixture was heated at 70° C. while being stirred for ten hours. After heating, the mixture was cooled to room temperature, and the insoluble substance was removed by means of filtering. The obtained filtrate was vacuum-concentrated, and diethyl ether is added in the residue, and then an insoluble material was removed by filtering. The obtained filtrate was vacuum-concentrated, and then 5-nonanone was obtained. The yield of the obtained 5-nonanone was determined and the result is shown in Table 1.

1. temperatureAfter heating
2. temperaturethe mixture was cooled to room temperature
3. customthe insoluble substance was removed by means
4. filtrationof filtering
5. concentrationThe obtained filtrate was vacuum-concentrated
6. additiondiethyl ether is added in the residue
7. customan insoluble material was removed
8. filtrationby filtering
9. concentrationThe obtained filtrate was vacuum-concentrated