Nonan-5-ol → 5-Nonanone
Reaction equation
IC1C=CC(C)=CC=1S(O)(=O)=O.OOS([O-])=O.[K+].[CH3:19][CH2:20][CH2:21][CH2:22][CH:23]([OH:28])[CH2:24][CH2:25][CH2:26][CH3:27]>[N+](C)([O-])=O>[CH3:19][CH2:20][CH2:21][CH2:22][C:23](=[O:28])[CH2:24][CH2:25][CH2:26][CH3:27]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 70 °C
Procedure
1.8 mg (0.006 mmol) of 2-iodo-5-methylbenzenesulfonic acid, prepared by Preparation Example 2, 1.11 g (1.8 mmol) of powdered Oxone (registered trademark) and 433 mg (3 mmol) of 5-nonanol were added in 3.75 ml of nitromethane, and the mixture was heated at 70° C. while being stirred for seven hours. The later treatment was carried out in the same way as in Example 1, and then 5-nonanone was obtained. The yield of the obtained 5-nonanone was determined and the result is shown in Table 1.
Sources & evidence
- ORD record
- ord-4cb98c8ce94e4964b8c972ef07d41266
- Source dataset
- uspto-grants-2013_03
- Patent number
- US08394995B2
Reaction notes
Loading…