1-Methylpiperazine → HCID 59606177, compound

HRID 1945716Notes

Reaction equation

HRID 1945716 reaction equation
[O:1]1[CH2:6][CH2:5][N:4]([C:7]2[C:8]3[S:25][C:24]([CH:26]=O)=[CH:23][C:9]=3[N:10]=[C:11]([C:13]3[CH:22]=[CH:21][CH:20]=[C:19]4[C:14]=3[CH:15]=[CH:16][CH:17]=[N:18]4)[N:12]=2)[CH2:3][CH2:2]1.[CH3:28][N:29]1[CH2:34][CH2:33][NH:32][CH2:31][CH2:30]1>>[CH3:28][N:29]1[CH2:34][CH2:33][N:32]([CH2:26][C:24]2[S:25][C:8]3[C:7]([N:4]4[CH2:3][CH2:2][O:1][CH2:6][CH2:5]4)=[N:12][C:11]([C:13]4[CH:22]=[CH:21][CH:20]=[C:19]5[C:14]=4[CH:15]=[CH:16][CH:17]=[N:18]5)=[N:10][C:9]=3[CH:23]=2)[CH2:31][CH2:30]1

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 86648239HCID 86648239, compound

Product 1

HCID 59606177HCID 59606177, compound

Procedure

Following General Procedure L for reductive amination, 4-morpholino-2-(quinolin-5-yl)thieno[3,2-d]pyrimidine-6-carbaldehyde and 1-methylpiperazine were reacted to give 120. LCMS m/z: 461.6 (MH+)

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-3bf45c19d8b14c99bc54133782370876
Source dataset
uspto-grants-2013_03
Patent number
US08394796B2

Reaction notes

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