Hydrochloric Acid → HCID 66790278, compound

Participants

Reaction Steps

To N-(1-{[4-cyclopropyl-2-(trifluoromethyl)phenyl]methyl}-1H-pyrazol-3-yl)-3-methyl-4-pyridinecarboxamide (for a preparation see Example 149)(20 mg) dissolved in methanol (1 ml) was added 4.0 M hydrochloride in 1,4-dioxane (0.4 ml, 1.60 mmol). The solvent was removed under a stream of nitrogen to give the title compound as an orange gum (38 mg); LCMS: (System 4) MH+=401, tRET=2.50 min.

Provenance & Evidence