HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminophenethyl alcohol → 6-(cyclohexylamino)-N-(4-(2-hydroxyethyl)phenyl)pyrimidine-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminophenethyl alcohol | HCID 66904 | — |
| Reactant | 6-(Cyclohexylamino)pyrimidine-4-carboxylic acid | HCID 59447075 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 6-(cyclohexylamino)-N-(4-(2-hydroxyethyl)phenyl)pyrimidine-4-carboxamide | HCID 25182780 | — |
Reaction Steps
Following the general method as outlined in Example 1, starting from 6-(cyclohexylamino)pyrimidine-4-carboxylic acid (Intermediate 4) and 2-(4-aminophenyl)ethanol (Fluka), the title compound was obtained as a white solid after trituration in acetonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399448B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-2c36ee658523465e8b2ed1be4fb5064a |
| Source note | uspto-grants-2013_03 |