Hydrogen chloride-ethyl acetate → HCID 66893209, compound

Participants

Reaction Steps

A solution of the obtained tert-butyl {2-[{[3-methoxy-4-oxo-5-(2-oxo-2-phenylethyl)-4,5-dihydrothieno[3,2-c]quinolin-2-yl]carbonyl}(methyl)amino]ethyl}carbamate (230 mg) and 4N hydrogen chloride ethyl acetate solution (8 mL) in ethyl acetate (15 mL) was stirred at room temperature for 2 hr. The obtained precipitate was collected by filtration, washed with diethyl ether, and dried under reduced pressure to give the title compound (178 mg, 48%) as a white powder.

Provenance & Evidence