HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 1485634, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | HCID 1485603 | HCID 1485603 | — |
| Solvent | Hydrogen Bromide | HCID 260 | — |
| Product | HCID 1485634 | HCID 1485634 | 38% |
Reaction Steps
2-(4-Fluoro-phenyl)-imidazo[1,2-a]pyridine-6-carboxylic acid methyl ester (example 1; 590 mg, 2.18 mmol) was heated in 5 ml hydrobromic acid (48%) and 15 ml acetic acid at 120° C. for 10 hours. The solid was filtered, washed and dried. Yield: 38%. MS: M+H+=257.04.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399476B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-d094ded1b3f6488ba8b9cbd0ca399b6e |
| Source note | uspto-grants-2013_03 |