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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1947889Generated: November 1, 2026

Trifluoroacetic acid → 7-amino-2-methyl-1-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid

https://huagongshe.com/reaction/1947889

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant7-[(Tert-butoxycarbonyl)amino]-2-methyl-1-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acidHCID 67256405—
Product7-amino-2-methyl-1-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acidHCID 67254279—

Reaction Steps

The title compound was prepared by deprotecting Compound 116C with TFA. The crude product was taken on to the next step without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399433B2
Source datasetuspto-grants-2013_03
ORD IDord-b0aba7bb9d2343b3939ab5a3f0f58a1b
Source noteuspto-grants-2013_03