反应详情

The title compound was prepared according to procedure for 2-Amino-5-fluoro-N-methylbenzamide (Compound 102A) using 3-methyl-5-nitroquinolin-4(1H)-one (Eur J Med Chem. 1992, 37, 547-570). 1H NMR (DMSO-d6, 400 MHz): δ=1.87 (d, J=0.76 Hz, 3H), 6.21 (dd, J=7.83, 1.01 Hz, 1H), 6.40 (dd, J=8.08, 1.01 Hz, 1H), 7.12 (t, J=8.08 Hz, 1H), 7.62 (dd, J=5.94, 0.88 Hz, 1H), 11.19 (d, J=5.05 Hz, 1H). MS (ES+): m/z 175.07 [MH+] (TOF, polar).