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HRID1948055

反应详情

EQUATION

反应方程式

HRID 1948055 的结构方程式

REACTANTS

反应物

3
结构：CC(=O)N1CCNCC1
HCID83795

1-Acetylpiperazine

C6H12N2O

结构：CN1Cc2c(C3CCC(N(C)C)CC3)ccc(N)c2C1=O
HCID67254285

未命名化合物

结构：CN1Cc2c(C3CCC(=O)CC3)ccc(N)c2C1=O
HCID67256125

7-Amino-2,3-dihydro-2-methyl-4-(4-oxocyclohexyl)-1H-isoindol-1-one

C15H18N2O2

PRODUCTS

生成物

1
结构：CC(=O)N1CCN(C2CCC(c3ccc(N)c4c3CN(C)C4=O)CC2)CC1
HCID67256455

未命名化合物

PROCEDURE

实验过程

The title product was prepared according to the procedure for Compound 233A using 7-amino-2-methyl-4-(4-oxocyclohexyl)-2,3-dihydro-1H-isoindol-1-one and 1-acetylpiperazine. 1H NMR (CDCl3, 400 MHz): δ=1.80-1.98 (m, 3H), 2.01-2.14 (m, 6H), 2.25 (d, J=19.20 Hz, 1H), 2.42-2.62 (m, 5H), 3.12-3.17 (m, 3H), 3.45-3.70 (m, 4H), 4.28-4.33 (m, 2H), 5.10 (br. s., 2H), 6.58 (d, J=8.08 Hz, 1H), 7.17 (d, J=8.34 Hz, 1H). MS (ES+): m/z 371.26 [MH+] (TOF, polar).