HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-(1-Amino-2-fluoro-ethyl)-4-ethyl-cyclohexanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4-(1-Amino-2,2,2-trifluoro-ethyl)-4-cyclopropylmethyl-cyclohexanol | HCID 67072905 | — |
| Product | 4-(1-Amino-2-fluoro-ethyl)-4-ethyl-cyclohexanol | HCID 58380838 | — |
Reaction Steps
99 mg of 55 were synthesized as mixture of stereoisomers as its hydrochloride from 236 mg (704 μmol) of 53 using the protocol described for the synthesis of compound 21. Rt=0.09, 0.14 min (Method P). Detected mass: 190.3 ([M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399482B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-88338d938c9848f2b5c96a474f9d042d |
| Source note | uspto-grants-2013_03 |