反应详情

Example 98 was synthesized using the reaction sequence as described for the alternative synthesis of Example 1 (step d and e). 60 mg of 4-(1-Amino-3-methoxy-propyl)-4-ethyl-cyclohexanol (59) and 53.9 mg of 7-chloro-6-fluoro-1-methoxy-isoquinoline (4) were used to give 43 mg of Example 98 as hydrochloride. Stereochemistry was not assigned. Rt=1.78 min (Method N). Detected mass: 393.3 (M+H+).

1. customExample 98 was synthesized
2. customas described for the alternative synthesis of Example 1 (step d and e)