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HRID1948352

反应详情

EQUATION

反应方程式

HRID 1948352 的结构方程式

REACTANTS

反应物

2
结构：O=S(Cl)Cl
HCID24386

Thionyl chloride

Cl2OS

结构：Cc1[nH]c(C(=O)N[C@@H]2CCN(c3ncc(C(=O)[O-])s3)C[C@@H]2F)c(Cl)c1Cl.[NH3+]C(CO)(CO)CO
HCID68517797

未命名化合物

2 次

PRODUCTS

生成物

1
结构：Cc1[nH]c(C(=O)Cl)c(Cl)c1Cl
HCID86038394

3,4-Dichloro-5-methyl-1H-pyrrole-2-carbonyl chloride

C6H4Cl3NO

PROCEDURE

实验过程

A solution of 10.4 g (54 mmol) of 3,4-Dichloro-5-methyl-1H-pyrrole-2-carboxylic acid (Intermediate 1) in 100 ml SOCl2 was heated at reflux for 30 min. Solvent was removed to afford product. NMR (CDCl3): 2.3 (s, 1H), 8.8 (s, 1H).

WORKUP

后处理

  1. temperatureat reflux for 30 min
  2. customSolvent was removed
  3. customto afford product