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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1948389Generated: November 2, 2026

Methyl iodide → tert-butyl N-[(2S)-2-methoxypropyl]carbamate

https://huagongshe.com/reaction/1948389

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantN-Boc-(S)-1-amino-2-propanolHCID 11789722—
Reactanttert-butyl [(2R)-2-methoxypropyl]carbamateHCID 86641515—
Producttert-butyl N-[(2S)-2-methoxypropyl]carbamateHCID 86643351—

Reaction Steps

The title compound was synthesized by using the method analogous to the synthesis of Intermediate 277 starting with tert-butyl [(2S)-2-hydroxypropyl]carbamate and alkylating it with methyl iodide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399489B2
Source datasetuspto-grants-2013_03
ORD IDord-983f2c69132347da8ca99934c476e524
Source noteuspto-grants-2013_03