Pyrrolidine → HCID 57475112, compound

Participants

Reaction Conditions

Reaction Steps

Pyrrolidine (1.95 g, 2.29 ml, 27.5 mmole), 1,2,3-triazole (2.07 g, 30 mmole) and molecular sieve 4 Å (7.14 g) were added to a solution of 1,4-dioxaspiro[4,5]decan-8-one (3.9 g, 25 mmole) in toluene (40 ml). The mixture was stirred for 7 days at 90° C. The solution was then decanted and immediately reacted further.

Provenance & Evidence