HRID1948635

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6422

未命名化合物

结构：Cc1ccc(S(=O)(=O)n2ccc(/C=C/C(=O)Nc3ccccc3N)c2)cc1

HCID11545400

未命名化合物

结构：CC(C)(C)OC(=O)Nc1ccccc1NC(=O)/C=C/c1ccn(S(=O)(=O)c2ccc(-c3ccccc3)cc2)c1

HCID86613978

未命名化合物

2 次

PRODUCTS

生成物

结构：Nc1ccccc1NC(=O)/C=C/c1ccn(S(=O)(=O)c2ccc(-c3ccccc3)cc2)c1

HCID11655175

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

The method used for preparation of this compound is analogous to the method described for compound 5. Starting materials: (2-{(E)-3-[1-(biphenyl-4-sulfonyl)-1H-pyrrol-3-yl]-allanoylamino}-phenyl)-carbamic acid tert-butyl ester (compound A7) (0.460 mmol), CH2Cl2 (50 ml), TFA (5 ml). Reaction conditions: room temperature, 18 hours.

WORKUP

后处理

customThe method used for preparation of this compound
customReaction conditions
customroom temperature, 18 hours

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-76d36b70da844296abedcd714b573b46
来源数据集: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08399505B2
来源说明: uspto-grants-2013_03

反应 SMILES

NC1C=CC=CC=1NC(=O)/C=C/C1C=CN(S(C2C=CC(C)=CC=2)(=O)=O)C=1.C(OC(=O)[NH:34][C:35]1[CH:40]=[CH:39][CH:38]=[CH:37][C:36]=1[NH:41][C:42](=[O:65])/[CH:43]=[CH:44]/[C:45]1[CH:49]=[CH:48][N:47]([S:50]([C:53]2[CH:58]=[CH:57][C:56]([C:59]3[CH:64]=[CH:63][CH:62]=[CH:61][CH:60]=3)=[CH:55][CH:54]=2)(=[O:52])=[O:51])[CH:46]=1)(C)(C)C.C(O)(C(F)(F)F)=O>C(Cl)Cl>[NH2:34][C:35]1[CH:40]=[CH:39][CH:38]=[CH:37][C:36]=1[NH:41][C:42](=[O:65])/[CH:43]=[CH:44]/[C:45]1[CH:49]=[CH:48][N:47]([S:50]([C:53]2[CH:54]=[CH:55][C:56]([C:59]3[CH:64]=[CH:63][CH:62]=[CH:61][CH:60]=3)=[CH:57][CH:58]=2)(=[O:52])=[O:51])[CH:46]=1