反应详情

To a solution of the product from Step C (1 g, 4.42 mmole) in dichloromethane (10 mL) was added triethylamine (0.54 g, 5.3 mmol) followed by methanesulfonyl chloride (0.6 g, 5.3 mmol) dropwise. The mixture was stirred at room temperature for 3-4 h. It was then washed with water and brine, and dried over magnesium sulfate, and concentrated to dryness to give the title compound as a colorless oil.

1. washIt was then washed with water and brine
2. dry with materialdried over magnesium sulfate
3. concentrationconcentrated to dryness