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HRID1948711

反应详情

EQUATION

反应方程式

HRID 1948711 的结构方程式

REACTANTS

反应物

2
结构：N#Cc1cnc(Cl)s1
HCID1485222

2-Chlorothiazole-5-carbonitrile

C4HClN2S

结构：CC(C)(C)OC(=O)NC1CCN(C(=O)OC2C3CC4CC2CC(C(N)=O)(C4)C3)C1
HCID75968129

未命名化合物

PRODUCTS

生成物

1
结构：N#Cc1cnc(NC2CCN(C(=O)OC3C4CC5CC3CC(C(N)=O)(C5)C4)C2)s1
HCID86653267

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from (3R) (1-carbamoyl-4-adamantyl) 3-(tert-butoxycarbonylamino)pyrrolidine-1-carboxylate isomer 2 following procedures analogous to those described in Example 33 using 2-chloro-5-cyanothiazole in Step 2. LC-MS Method 1 tR=1.32 min, m/z=415; 1H NMR (CD3OD) 1.55 (2H), 1.85-2.15 (12H), 2.25 (m, 1H), 3.35-3.80 (4H), 4.40 (br s, 1H), 4.78 (s, 1H), 7.74 (s, 1H).